Saturday, November 24, 2012

ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usThu, 22 Nov 2012 23:24:21 ESTThu, 22 Nov 2012 23:24:21 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.Scientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htmQuick test speeds search for Alzheimer's drugs: Compound restores motor function and longevity to fruit flieshttp://www.sciencedaily.com/releases/2012/11/121115152655.htm Researchers report that an efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease.Thu, 15 Nov 2012 15:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115152655.htmProtein-making machinery can switch gears with a small structural change process; Implications for immunity and cancer therapyhttp://www.sciencedaily.com/releases/2012/11/121115133414.htm For the past several years, research has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins. In a new study, scientists have shown that this enzyme can actually also work in another fundamental process in humans.Thu, 15 Nov 2012 13:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121115133414.htmPlant derivative, tanshinones, protects against sepsis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121115133312.htm Researchers have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis.Thu, 15 Nov 2012 13:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121115133312.htmStructure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugshttp://www.sciencedaily.com/releases/2012/11/121115132903.htm Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are important enzymes that are involved in maintaining the structure of DNA and chromosome segregation during both replication and transcription of DNA. One of these enzymes, topoisomerase II alpha, is involved in the replication of DNA and cell proliferation, and is highly expressed in rapidly dividing cancer cells.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132903.htmNewly discovered enzyme important in the spreading of cancerhttp://www.sciencedaily.com/releases/2012/11/121115132901.htm Enzyme hunters at UiO have discovered the function of an enzyme that is important in the spreading of cancer. Cancer researchers now hope to inhibit the enzyme.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132901.htmGenetics point to serious pregnancy complication, pre-eclampsiahttp://www.sciencedaily.com/releases/2012/11/121115132613.htm New research has revealed a genetic link in pregnant moms - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.Thu, 15 Nov 2012 13:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115132613.htmMolecular mechanisms underlying stem cell reprogramming decodedhttp://www.sciencedaily.com/releases/2012/11/121115132344.htm Thanks to some careful detective work, scientist better understand just how iPS cells form ? and why the Yamanaka process is inefficient, an important step to work out for regenerative medicine. The findings uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132344.htmSurprising genetic link between kidney defects and neurodevelopmental disorders in kidshttp://www.sciencedaily.com/releases/2012/11/121115132342.htm About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study has shown.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132342.htmEven moderate drinking in pregnancy can affect a child's IQhttp://www.sciencedaily.com/releases/2012/11/121114172833.htm Relatively small levels of exposure to alcohol while in the womb can influence a child's IQ, according to a new study using data from over 4,000 mothers and their children.Wed, 14 Nov 2012 17:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121114172833.htmGene nearly triples risk of Alzheimer's, international research team findshttp://www.sciencedaily.com/releases/2012/11/121114171710.htm A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team of researchers. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171710.htmDiscovery could lead to faster diagnosis for some chronic fatigue syndrome caseshttp://www.sciencedaily.com/releases/2012/11/121114171708.htm For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome - testing for antibodies linked to latent Epstein-Barr virus reactivation.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171708.htmResearch breakthrough could halt melanoma metastasis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121114153227.htm In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.Wed, 14 Nov 2012 15:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114153227.htmPig genomes provide massive amount of genomic data for human healthhttp://www.sciencedaily.com/releases/2012/11/121114134512.htm Researchers provide a whole-genome sequence and analysis of number of pig breeds, including a miniature pig that serves a model for human medical studies and therapeutic drug testing.Wed, 14 Nov 2012 13:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121114134512.htmRare parasitic fungi could have anti-flammatory benefitshttp://www.sciencedaily.com/releases/2012/11/121114134054.htm Caterpillar fungi are rare parasites found on hibernating caterpillars in the mountains of Tibet. For centuries they have been highly prized as a traditional Chinese medicine - just a small amount can fetch hundreds of dollars.Wed, 14 Nov 2012 13:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121114134054.htmCancer therapy: Nanokey opens tumors to attackhttp://www.sciencedaily.com/releases/2012/11/121114113803.htm There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.Wed, 14 Nov 2012 11:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121114113803.htmHigh sperm DNA damage a leading cause of 'unexplained infertility', research findshttp://www.sciencedaily.com/releases/2012/11/121114113235.htm New research has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility': high sperm DNA damage.Wed, 14 Nov 2012 11:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114113235.htmA risk gene for cannabis psychosishttp://www.sciencedaily.com/releases/2012/11/121114083928.htm The ability of cannabis to produce psychosis has long been an important public health concern. This concern is growing in importance as there is emerging data that cannabis exposure during adolescence may increase the risk of developing schizophrenia, a serious psychotic disorder. Further, with the advent of medical marijuana, a new group of people with uncertain psychosis risk may be exposed to cannabis.Wed, 14 Nov 2012 08:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121114083928.htmBacterial DNA sequence used to map an infection outbreakhttp://www.sciencedaily.com/releases/2012/11/121113214635.htm For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close. Researchers used advanced DNA sequencing technologies to confirm the presence of an ongoing outbreak of methicillin-resistant Staphylococcus aureus (MRSA) in a Special Care Baby Unit in real time. This assisted in stopping the outbreak earlier, saving possible harm to patients. This approach is much more accurate than current methods used to detect hospital outbreaks.Tue, 13 Nov 2012 21:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121113214635.htmGenetic variation may modify associations between low vitamin D levels and adverse health outcomeshttp://www.sciencedaily.com/releases/2012/11/121113161506.htm Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such as hip fracture, heart attack, cancer, and death.Tue, 13 Nov 2012 16:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121113161506.htmNew type of bacterial protection found within cells: Novel immune system response to infections discoveredhttp://www.sciencedaily.com/releases/2012/11/121113143656.htm Biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.Tue, 13 Nov 2012 14:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121113143656.htmGlutamate neurotransmission system may be involved with depression riskhttp://www.sciencedaily.com/releases/2012/11/121113134807.htm Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate appear to increase the risk of depression.Tue, 13 Nov 2012 13:48:48 ESThttp://www.sciencedaily.com/releases/2012/11/121113134807.htmTargeting downstream proteins in cancer-causing pathway shows promise in cell, animal modelhttp://www.sciencedaily.com/releases/2012/11/121113134230.htm The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell?s powerhouse, making it dependent on the amino acid glutamine for survival. Depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc. Using Myc-active neuroblastoma cells, a team three priotein executors of the glutamine-starved cell, representing a downstream target at which to aim drugs. Roughly 25 percent of all neuroblastoma cases are associated with Myc-active cells.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134230.htmEven low-level radioactivity is damaging, scientists concludehttp://www.sciencedaily.com/releases/2012/11/121113134224.htm Even the very lowest levels of radiation are harmful to life, scientists have concluded, reporting the results of a wide-ranging analysis of 46 peer-reviewed studies published over the past 40 years. Variation in low-level, natural background radiation was found to have small, but highly statistically significant, negative effects on DNA as well as several measures of health.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134224.htmLoss of essential blood cell gene leads to anemiahttp://www.sciencedaily.com/releases/2012/11/121113122220.htm Scientists have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood. The findings promise to advance the biomedical community's understanding and treatment of human anemias and mitochondrial diseases, both known and unknown.Tue, 13 Nov 2012 12:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121113122220.htmWatching the developing brain, scientists glean clues on neurological disorderhttp://www.sciencedaily.com/releases/2012/11/121113122133.htm Researchers have tracked a gene's crucial role in orchestrating the placement of neurons in the developing brain. Their findings help unravel some of the mysteries of Joubert syndrome and other neurological disorders.Tue, 13 Nov 2012 12:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121113122133.htmSolving the mystery of aging: Longevity gene makes Hydra immortal and humans grow olderhttp://www.sciencedaily.com/releases/2012/11/121113091953.htm Why do we get older? When do we die and why? Is there a life without aging? For centuries, science has been fascinated by these questions. Now researchers have examined why the polyp Hydra is immortal -- and unexpectedly discovered a link to aging in humans.Tue, 13 Nov 2012 09:19:19 ESThttp://www.sciencedaily.com/releases/2012/11/121113091953.htmMen and women battle for ideal height: Evidence of an intralocus sexual conflict currently raging in human DNAhttp://www.sciencedaily.com/releases/2012/11/121113083536.htm A battle about the ideal height would appear to be raging in men's and women's genes. A researcher in Sweden has shown that this conflict is leading to a difference in reproductive success between men and women of varying height.Tue, 13 Nov 2012 08:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121113083536.htmCatch and release of rare cancer cells inspired by jellyfishhttp://www.sciencedaily.com/releases/2012/11/121112171314.htm A research team has developed a novel device that may one day have broad therapeutic and diagnostic uses in the detection and capture of rare cell types, such as cancer cells, fetal cells, viruses and bacteria.Mon, 12 Nov 2012 17:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121112171314.htmJellyfish-inspired device that captures cancer cells from blood samples could enable better patient monitoringhttp://www.sciencedaily.com/releases/2012/11/121112171312.htm Tumor cells circulating in a patient's bloodstream can yield a great deal of information on how a tumor is responding to treatment and what drugs might be more effective against it. But first, these rare cells have to be captured and isolated from the many other cells found in a blood sample. Scientists are now working on microfluidic devices that can isolate circulating tumor cells.Mon, 12 Nov 2012 17:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121112171312.htmNew cause of thyroid hormone deficiency discoveredhttp://www.sciencedaily.com/releases/2012/11/121112135615.htm Researchers have discovered a new cause for thyroid hormone deficiency, or hypothyroidism. The scientists identified a new hereditary form of hypothyroidism that is more prevalent in males than in females. This sex bias shone a light on where to look for the underlying cause.Mon, 12 Nov 2012 13:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121112135615.htmGenetic link between pancreatitis and alcohol consumptionhttp://www.sciencedaily.com/releases/2012/11/121112135520.htm A new study reveals a genetic link between chronic pancreatitis and alcohol consumption. Researchers found a genetic variant on chromosome X near the claudin-2 gene (CLDN2) that predicts which men who are heavy drinkers are at high risk of developing chronic pancreatitis.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135520.htmHumans are slowly but surely losing intellectual and emotional abilities, article suggestshttp://www.sciencedaily.com/releases/2012/11/121112135516.htm Human intelligence and behavior require optimal functioning of a large number of genes, which requires enormous evolutionary pressures to maintain. A provocative theory suggests that we are losing our intellectual and emotional capabilities because the intricate web of genes endowing us with our brain power is particularly susceptible to mutations and that these mutations are not being selected against in our modern society.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135516.htmHow chronic inflammation can cause cancerhttp://www.sciencedaily.com/releases/2012/11/121112135512.htm A new study has found that interleukin-15 (IL-15) alone can cause large granular lymphocytic (LGL) leukemia, a rare and usually fatal form of cancer. The researchers developed a treatment for the leukemia that showed no discernible side effects in an animal model. The study shows that IL-15 is also overexpressed in patients with LGL leukemia and that it causes similar cellular changes, suggesting that the treatment should also benefit people with the malignancy.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135512.htmList of diseases spread by deer tick grows, including malaria-like problems and potentially fatal encephalitishttp://www.sciencedaily.com/releases/2012/11/121112135510.htm An emerging tick-borne disease that causes symptoms similar to malaria is expanding its range in areas of the northeast where it has become well-established, according to new research.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135510.htmParkinson's disease: Compensation in the brain could lead to new treatmenthttp://www.sciencedaily.com/releases/2012/11/121112135404.htm New evidence indicates that Parkinson's disease is preceded by a period during which healthy regions of the brain take over the functions of damaged ones.Mon, 12 Nov 2012 13:54:54 ESThttp://www.sciencedaily.com/releases/2012/11/121112135404.htm

Source: http://www.sciencedaily.com/rss/health_medicine/genes.xml

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Many home loan programs tend to be addressed by finance institutions or other expert lenders. They could make use of a variety of criteria to determine in case your potential consumer is actually skilled for a financial loan. Past credit rating is virtually usually regarded, together with existing earnings as well as assets. The objective of the credit can be an issue-a established investment chance could have much more appeal than an misguided idea for any new eating place. 1 essential point could be the profits to debt percentage in the customer. May the customer manage to pay for the bank loan back along with interest? Skilled loan providers basically 'sell' money, so consumers should be aware just how much financing really 'costs' when it comes to real money.

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Source: http://vikcheroky.livejournal.com/370864.html

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One Direction's 2nd CD hits No. 1, sells 540,000

NEW YORK (AP) ? One Direction's "Take Me Home" is the taking the boys to the top of the charts ? and to new heights.

The group's sophomore album has sold 540,000 in its first week, according to Nielsen SoundScan. It's the year's third-highest debut behind Taylor Swift's "Red," which sold 1.2 million units its first week earlier this month, and Mumford & Sons' "Babel," which sold more than 600,000 albums in September in its debut week.

"We just want to say a massive thanks to all the fans who have supported us," band member Harry Styles, 18, said in an interview Tuesday from London. "We can send tweets and thank them, but 140 characters is never going be enough to say how much it means."

The album also debuted at No. 1 in the United Kingdom this week and is No. 1 in more than 30 countries, Columbia Records said Wednesday. The fivesome's debut, "Up All Night," came in at No. 2 in the United Kingdom last year; it was just released in March in America, where it hit No. 1 and has achieved platinum status.

"We were a little bit nervous about how people were going to take it," 19-year-old Niall Horan said of the new album during tour rehearsals. "Everyone gets that second album syndrome."

They say though they're excited, they won't be celebrating too much: "We're finishing rehearsing soon and we're going home to bed."

One Direction, who placed third on the U.K. version of "The X Factor" in 2010, is signed to Simon Cowell's Syco label imprint. In just a year, the band has become worldwide sensations, thanks to its feverish fans. They released a book and have a 3D movie planned. They also made the cut for Barbara Walters' most fascinating people of 2012 list, which includes New Jersey Gov. Chris Christie and U.S. gold medalist Gabby Douglas.

One Direction says those experiences have helped the group mature.

"We've been working hard. We're starting to grow up," Horan said. "We're still young, but we've passed the initial teenage years. ...We've grown up quite quick in the job we have to do and we became a lot more independent."

The group ? which includes Zayn Malik, Liam Payne and Louis Tomlinson ? will launch a worldwide tour in February. They hope to work with Katy Perry and are still trying to adjust to the celebrity and fame that has taken over their lives.

"I can see how it gets to people. I guess it's quite easy to get wrapped up in it all," Styles said. "We do the same things every other lad our age does. We go out, we have fun, we meet girls and stuff like that. Sometimes it gets written about, which, yeah, we think about it and it's absolutely crazy. It's still a bit weird thinking that that's the way it is."

___

Online:

http://www.onedirectionmusic.com/us/home/

___

Follow Music Mesfin on Twitter at http://twitter.com/MusicMesfin

Source: http://news.yahoo.com/one-directions-2nd-cd-hits-no-1-sells-040506773.html

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Thursday, November 22, 2012

Weak muscles in teen years linked to early death in men - 8 News ...

TUESDAY, Nov. 20 (HealthDay News) -- Men who had low muscle strength during their teen years are at increased risk for early death from several major causes, a new study contends.

The researchers from the Karolinska Institute in Sweden found that, for men, the effect of having low muscle strength in youth was similar to the well-known risk factors for early death such as being overweight or having high blood pressure.

The findings point to the need for young people, particularly those with very low strength, to get regular exercise to improve their muscular fitness, the study authors said in the report, published in the Nov. 20 online edition of the BMJ.

The study included more than 1 million Swedish males aged 16 to 19 who were followed for 24 years. The participants underwent strength tests at the start of the study. Early death was defined as death before age 55.

During the follow-up, 2.3 percent (more than 26,000) of the men died. The most common cause of death was suicide (22 percent), while cancer accounted for nearly 15 percent of deaths and cardiovascular diseases caused just less than 8 percent of deaths, the investigators found.

Adults who had high muscular strength as teens had a 20 percent to 35 percent lower risk of early death from any cause and also from cardiovascular diseases, independently of blood pressure or body-mass index (a measurement of fat based on height and weight), the results indicated.

In addition, those who were the strongest as teens also had a 20 percent to 30 percent lower risk of early death from suicide and were 65 percent less likely to be diagnosed with a mental health disorder, such as schizophrenia or mood disorders.

When the researchers looked at death rates from any cause, the rates ranged from 122.3 per 100,000 person years for those with the lowest muscle strength and 86.9 per 100,000 person years for those with the greatest muscle strength. Death rates for cardiovascular diseases were 9.5 and 5.6 per 100,000 person years, respectively, and for suicide were 24.6 and 16.9 per 100,000 person years, respectively.

The findings suggest that lower muscle strength in teens "is an emerging risk factor for major causes of death in young adulthood, such as suicide and cardiovascular diseases," study author Finn Rasmussen and colleagues concluded in a journal news release.

The results also point to the importance of exercise for children and teens, the authors noted.

The study found an association between low muscle strength during teen years and early death in men; it did not prove cause-and-effect.

More information

The Nemours Foundation has more about strength training for children.

Copyright ? 2012 HealthDay. All rights reserved.

Source: http://www.8newsnow.com/story/20157000/weak-muscles-in-teen-years-linked-to-early-death-in-men

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House panel: Let courts decide Fast and Furious

WASHINGTON (AP) ? A House panel said Wednesday it believes federal courts have the authority to decide a dispute in which Attorney General Eric Holder is refusing to provide Congress with Justice Department documents about a botched criminal investigation into gun-trafficking on the Southwest border.

In a 65-page filing about Operation Fast and Furious, the House Oversight and Government Reform Committee said federal courts have routinely reviewed the validity of congressional inquiries. The lawyers for the House said Holder's contention that courts cannot adjudicate political disputes would permanently shut the courthouse doors to virtually all disputes between the executive and legislative branches.

In court papers filed last month, the Justice Department said the courts must defer to the time-tested political process of stepping aside and letting Congress and the executive resolve their political differences.

"Labeling a dispute 'political' is not a legal argument; it is a talking point masquerading ? poorly ? as an argument," said the filing for the committee chaired by Rep. Darrell Issa, R-Calif. "Federal courts have been deciding cases regarding the executive's compliance with subpoenas since the earliest days of the Republic."

In the dispute over Operation Fast and Furious, President Barack Obama has invoked what is known as executive privilege. The Republican-run House in June voted Holder in contempt of Congress for refusing to turn over subpoenaed records that might explain what led the Justice Department to reverse course after initially denying that federal agents had used a controversial tactic called gun-walking in the failed law enforcement operation.

"It is no exaggeration to say that if the courthouse door is closed to Congress in subpoena enforcement cases of this nature, the executive's incentive to respond to congressional requests for information largely will disappear and, with it, effective congressional oversight of the executive branch," the House's court papers said.

In Fast and Furious, agents from the Bureau of Alcohol, Tobacco, Firearms and Explosives abandoned the agency's usual practice of intercepting all weapons they believed to be illicitly purchased, often as soon as they were taken out of gun shops. Instead, the goal of the gun-walking approach was to track such weapons to high-level arms traffickers who long had eluded prosecution, and to dismantle their networks.

Federal agents lost track of many of the guns. The operation identified more than 2,000 illicitly purchased weapons, and some 1,400 of them have yet to be recovered.

Source: http://news.yahoo.com/house-panel-let-courts-decide-fast-furious-230156413.html

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Wednesday, November 21, 2012

How to Choose the Right Bankruptcy Attorney | Modern Day Finance

Posted by Deborah Dera on Nov 21, 2012 in Bankruptcy | 0 comments

You?ve decided to file for bankruptcy. You?re certainly not alone. Your biggest concern now that you?ve decided to explore filing is to find a bankruptcy attorney you can really trust to get you through the process. Here are a few things to keep in mind as you look around.

Find a Lawyer that Specializes in Bankruptcy

Bankruptcy laws are complex and vary from state to state. While there are tons of legal offices with lawyers specializing in many types of law, your best best is to find a lawyer who specializes in bankruptcy only. The laws are constantly changing and you?ll want to feel comfortable in knowing that you are with someone who knows the process inside out.

Free Consultations & Ultimate Fees

It?s common knowledge that lawyers like to charge for their time, but bankruptcy lawyers are a little different. Most will charge you a flat rate that includes the actual court filing costs plus their own service fees. The cost I spent on my own bankruptcy was approximately $1,500. That seems like a lot, but once your lawyer has told you to stop paying on the bills you?re filing against, you shouldn?t have a tough time scraping whatever amount is needed together.

Don?t, however, settle for a lawyer who won?t give you a free consultation. My bankruptcy lawyer spoke to me, at length, on the phone before setting up a formal consultation with a representative in his office. Some lawyers offer in-office consultations. I did have a meeting with a lawyer in the office, and a nominal fee that was put towards my total cost was charged.

Remember, the cheapest lawyer isn?t always the best lawyer. While it?s important to compare rates, there are other factors to consider as well.

Ask the Right Questions

You already feel vulnerable and the bankruptcy process isn?t exactly the most exciting or calming thing on earth. That said, you still have the right to ask your potential attorney some interview-style questions. Ask him how many bankruptcy cases he handles annually, what certifications he has, and who else in the office you will be working with aside from him. Most lawyers have clerical staff who will be the ones actually guiding you through the paperwork. I was surprised to have a different face show up at my meeting of creditors, too. It helps to know who you?ll be working with.

It?s best to choose an attorney local to you so that you can easily get to the office when it?s time to do paperwork. Trust me when I say that the thick pile of papers that actually makes up your bankruptcy petition is not something you?ll want to sort through on your own. At the end of the day, you?ll want to feel comfortable with the person you?re divulging your financial history to. If you?re not, simply move on. There are plenty of lawyers out there willing to help.

Source: http://www.moderndayfinance.com/how-to-choose-the-right-bankruptcy-attorney

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S. Africa's Tiger Brands to up stake in Dangote Flour

JOHANNESBURG (Reuters) - South African consumer goods group Tiger Brands is offering to buy out some minority shareholders in Nigeria's Dangote Flour Mills as it expands in fast-growing African markets.

Earlier this year Tiger Brands bought a 63 percent stake in the flour and pasta maker in its third and biggest deal yet in Nigeria, Africa's most populous country and second-largest economy, which is seen as a growth area for consumer and food products.

Owner Aliko Dangote's holding firm Dangote Industries Ltd kept a 10 percent shareholding in the flour mill after Tiger Brands' purchase.

Tiger Brands said in a presentation on its full-year earnings that it is making an offer to minorities in Dangote Flour, which is expected to be completed by March next year.

"We will go up to a maximum of 70 percent in total, leaving the balance in Nigerian hands," Tiger Brands' chief executive Peter Matlare told Reuters after the presentation.

Tiger Brands, a maker of bread, breakfast cereal and energy drinks, expanded outside its home base last year with acquisitions in Nigeria and Ethiopia.

Matlare said the company will seek acquisitions in Africa, as well as growing its own business.

Tiger Brands posted a 7 percent rise in full-year earnings, helped by higher prices. It said diluted headline earnings per share for the year to end September reached 1,654.2 cents from 1,545 cents last year.

Headline earnings, the main profit gauge in South Africa, exclude certain one-off items.

The company said revenue rose 11 percent to 22.7 billion rand. It declared a final dividend of 555 cents per share.

But the company said it expected 2013 to be a challenging year as consumers remain under pressure, with economic growth sluggish, unemployment high and inflation accelerating.

Tiger Brands shares were down 1.5 percent at 273.67 rand at 1055 GMT.

Source: http://news.yahoo.com/tiger-brands-reports-rise-full-earnings-053234864--finance.html

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